Effects of turmeric powder on intestinal and biliary functions: The influence of curcuminoids concentration on spontaneous contractility

Two turmeric food powders (C1 and C2) were studied for curcuminoid content their effects on the guinea pig intestinal tract in vitro. C1 contained a higher than C2 (5.22% vs 2.31%). increased gallbladder (∼10%) biliary smooth muscle tone (∼15%), without affecting sphincter of Oddi contractility. was more effective lowering ileum (–22% −37%), whereas reverse occurred colon (-50% −20%). Standard Fast Fourier transforms absolute powers analysis frequency bands highlighted that, bile duct, induced contractions variability ampler oscillations low-frequency waves. At sphincter, had biphasic effect, increasing then drastically decreasing oscillations. The same with ileum, while both samples reduced fluctuations colon.